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Here Is a Human Being: At the Dawn of Personal Genomics (Inglese) Copertina rigida – 1 dic 2010

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Book by Angrist Misha

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Amazon.com: HASH(0xb534f6a8) su 5 stelle 12 recensioni
13 di 14 persone hanno trovato utile la seguente recensione
HASH(0xaaf59960) su 5 stelle Here is a really great read 20 novembre 2010
Di Marc H. - Pubblicato su Amazon.com
Formato: Copertina rigida
Misha Angrist's "Here is a human being: At the dawn of personal genomics" is a must read for anyone interested in knowing what's in his or her own DNA. I would further highly recommend it to anyone in the medicine or genetics field. This is the personal story of Misha Angrist who became one of the ten individuals that had their entire human genome sequenced through Dr. George Church's Personal Genome Project. This book delves into the humanity of the great question of "what DO I want to know about my DNA?" How comfortable are any of us with the knowledge that our DNA can suggest that we have inherited a predisposition to cancer or some other malady? The author does a wonderful job of approaching these questions from a myriad of ethical, legal, societal, and medical directions in a captivating, first-person narrative. This book has forever changed my views on what I would and would not want to know about my own DNA. What makes this book such a nice read is that it is a story full of fascinating people. Despite the impossibly complex science that goes into determining one's DNA sequence, the book never becomes trapped in technical speak (although the technical terminology, when present, is both accurate and accessible). I have previously read "The genome war" by James Shreeve and I consider this Angrist book to be the next chapter in the ever-unfolding genomic saga of the day.
5 di 5 persone hanno trovato utile la seguente recensione
HASH(0xaa5473b4) su 5 stelle Interesting Read 12 dicembre 2011
Di RJ Blain - Pubblicato su Amazon.com
Formato: Formato Kindle
I am not someone who reads a lot of science material, at least for pleasure reading, but I found this book to be very interesting. It does more than just talk about science. It talks about the important people behind the sciences, which interest me a lot more than the actual sciences. There is plenty of science in this book, which is (for the most part) very well explained. There were times I found myself doing a little research to have a better understanding of what the sciences were about, but I feel that this book was good for those who don't necessarily want to know everything about the sciences but want to know about the process of how genomics came to the public.

When I started reading this book, I expected something a lot different than what i got, but I feel that this is a good thing. I don't think this book will necessarily appeal to science lovers and researchers; it is light compared to the hefty tomes that more suit those wanting in-depth knowledge of any subject. It covers the basics so that it can be brought to the average person who *isn't* a scientist, which is what appealed to me as I read it.

Best of all, you realistically only need middle or high school level science to understand what is going on in the book, which opens this title to the average teenager, if that sort of research is up their alley. I also like the general message of this book, and how it pursues the potential impact of genomics on base society.
2 di 2 persone hanno trovato utile la seguente recensione
HASH(0xaaf5d2f4) su 5 stelle What if you knew your genome sequence? What would it change? 29 luglio 2011
Di PDF - Pubblicato su Amazon.com
A great book by a thoughtful and honest member of the PGP, one of the first people on the planet to have his genome sequenced. Unlike James Watson, a mid-80s legend with most of his life behind him, Misha Angrist is just like you or me - OK, maybe a little bit smarter and a much better writer. He has a wife, kids, a job, health insurance and self doubts. His honest accounting of his decision to become part of the personal genome project, and what he found out from looking at his whole genome feels like the kind of journey of discovery any of us might go through.

If you've wondered what all this "genome" stuff is all about, the author also narrates the human genome project, and how scientists have achieved the capability to affordably sequence a human being. He's met all the big names, the legends, the people on the cutting edge of science and he shares his impressions and interactions.

It's a great book, a fun read, and a journey of introspection for the author and for the reader.
3 di 4 persone hanno trovato utile la seguente recensione
HASH(0xaa547384) su 5 stelle Not bad but i've read better on the subject of personal genomics and gene testing 25 giugno 2011
Di Raina B. - Pubblicato su Amazon.com
Formato: Formato Kindle
While i think this book is written well and def is interesting in parts, I didn't walk away feeling like I gained much. This is in contradiction to another book on the subject I read called 'Outsmart Your Genes' by Brandon Colby, MD. Outsmart Your Genes: How Understanding Your DNA Will Empower You to Protect Yourself Against Cancer, Alzheimer's, Heart Disease, Obesity, and Many Other Conditions In this book the author Dr. Colby, who is both a respected geneticist and a practicing doctor that is one of the key players in this new field of predictive medicine, also discussed personal genomics in-depth throughout his book. But instead of just an overview he actually says exactly how it is useful today for someone like me (and i know nothing about gene testing!). After reading that book I purchased gene tests for both myself and my child through my doctor (because Dr. Colby's book made me understand how and why to do this) and the results really changed my life because something very signifciant was detected and my doctor thinks it may have saved the life of my son.

'Here is a Human Being' however didn't really provide this type of useful info but instead was just an overview and also spoke down about a lot of things so it made it seem like gene testing was useless whereas i can tell you from personal experience it is not. I guess maybe this book wasn't meant to really give me actionable info but after reading 'Outsmart Your genes' i felt that i not only already learned what i needed to know about the topic and was aware of some of the issues with gene testing but also i knew exactly how it applied to me today and how i could use it to protect my life.
HASH(0xaaf61738) su 5 stelle A Worthy Read 7 giugno 2012
Di P. F. Anderson - Pubblicato su Amazon.com
Blogged here: [...]

Here is a Human Being really needs to be read like a story, and it also calls out to be read like deconstructing a piece of jewelry or craftwork prior to replicating the design in a new media. It has both a natural flow, and a sense of profoundly subtle (almost invisible) craft and design.

There is no conceptual organizer given at the beginning of the book, like the Dramatis personae or a timeline. There is no cognitive structure to help me understand this is where I began, this is how the book is evolving, and this is the expected path for getting there. My masters research focused on applying an educational technique that was then called an "advance organizer." The oversimplified rule of thumb was tell them what you're going to say, say it, and then tell them what you told them. Me, I like to include something about WHY, why it's important, why it's valuable information to you, what are *you* going to get out if it. In this case, he might also want something on what the value was to him.

Through reading this, I've ended up reading the personal stories provided on a number of the personal genomic corporate websites, but I just can't trust them. They read a bit fake, like the marketing pieces they are. Misha doesn't. Misha sounds honest and real. He says, I had these questions, I had these doubts, I had these concerns. I did it anyway. This is why. This is what I found, what I learned, how I learned it.

The book has important, excellent, well-crafted content. It tells a critical story. It tells a complex story. I agree that you don't need to be a scientist to understand it. However, it doesn't always include the context to make it easily accessible or an easy read. The story parts read easily, but without the cognitive construct into which to fit the pieces, I am having to create that myself as I go along. I am kind of mentally outlining the book as we go. Just when I think I know where he's headed, and I settle in to just focus on reading, he changes direction. I react, "Whoa, that isn't what I expected, what's going on now?" and I start again digging into footnotes and background research.

My approach to reading this book might have been a mistake. It certainly took long enough! It might be easier to see the most important part of the book, the story. The story only gets more intense and engaging as the book progresses. And it has a worthy ending.

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