- Copertina rigida: 273 pagine
- Editore: Henry Holt & Co (8 aprile 2014)
- Lingua: Inglese
- ISBN-10: 0805098100
- ISBN-13: 978-0805098105
- Peso di spedizione: 476 g
- Media recensioni: 5.0 su 5 stelle Visualizza tutte le recensioni (2 recensioni clienti)
- Posizione nella classifica Bestseller di Amazon:
Missing Microbes: How the Overuse of Antibiotics Is Fueling Our Modern Plagues (Inglese) Copertina rigida – 8 apr 2014
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A critically important and startling look at the harmful effects of overusing antibiotics, from the field's leading expert Tracing one scientist's journey toward understanding the crucial importance of the microbiome, this revolutionary book will take readers to the forefront of trail-blazing research while revealing the damage that overuse of antibiotics is doing to our health: contributing to the rise of obesity, asthma, diabetes, and certain forms of cancer. In "Missing Microbes," Dr. Martin Blaser invites us into the wilds of the human microbiome where for hundreds of thousands of years bacterial and human cells have existed in a peaceful symbiosis that is responsible for the health and equilibrium of our body. Now, this invisible eden is being irrevocably damaged by some of our most revered medical advances--antibiotics--threatening the extinction of our irreplaceable microbes with terrible health consequences. Taking us into both the lab and deep into the fields where these troubling effects can be witnessed firsthand, Blaser not only provides cutting edge evidence for the adverse effects of antibiotics, he tells us what we can do to avoid even more catastrophic health problems in the future.
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Principali recensioni dei clienti
5 stelle all’autore e al libro
Libro affascinante, ricco di aneddoti e storie cliniche che rendono la lettura coinvolgente e appassionante.
L’autore, stimato ricercatore e direttore del Human Microbiome Project alla NYU, ha una ottima capacità di raccontare, informare, coinvolgere il lettore in osservazioni, scoperte e congetture che cambiano il nostro modo di vedere il mondo vivente.
Verso la conclusione diviene visionario e un po’ apocalittico; ma ciò è parte dello scopo del libro.
3 stelle alla versione Kindle (versione 5.1 per iPad)
Il 20% del libro (equivalente a circa 58 pagine a stampa) è costituito da note.
Note che non sono, come spesso capita, noiosi riferimenti accademici, ma sono ricche integrazioni al testo principale.
Nell'edizione Kindle le note non sono visibili durante la lettura del testo e, una volta scoperta la loro esistenza alla fine del documento, non è possibile risalire al testo al quale si riferiscono. In tal modo si perde quasi totalmente l’utilità delle note.
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The book begins with several chapters that explain microbiology and how microbes are aligned with the human body. For instance, there are millions of microbes living in your intestinal tract, but they are not harmful; in fact they may be very beneficial. Early and frequent use of antibiotics can disrupt this natural ecosystem causing a myriad of problems.
There is also information on how we obtain our microbiological flora. For instance, microbes are passed from a mother to a baby during birth. As the baby exits the birth canal, it is coated in the naturally occurring bacteria that is found there normally. In addition, the newborn will pick up bacteria from nursing and from being handled by the mother. All of this is normal, and healthy, but overuse of antibiotics maybe causing disruption of the normal process.
In information presented that was startling, the author has linked a bacteria found in the stomach, and thought to cause ulcers, to an increase in the number of cases of gastrointestinal esophageal reflux disease. When it was first proven that the bacteria in question was responsible for ulcers, doctors went on a spree to eradicate it from adults. What followed was a large increase in the number of cases of GERD, in which gastric acid backs up into the esophagus and thereby damages it. In addition, the eradication of that bacteria may lead to it being eradicated from infants, which is a possible cause for the increase in asthma cases being seen in children.
The author also presents evidence of obesity being linked, quite significantly, to the use of antibiotics in the food supply and in early childhood. It is an interesting correlation, and may provide the answer to why there has been such a large increase in the number of obese children.
These are only some of the evidence presented and I am oversimplifying the information because of the brevity of a review. The information is fascinating, and may unlock the secrets to a number of "new plagues" as the author describes these diseases.
The book is very well written and is written with the lay person in mind. I had no problem following the science presented in the book and found the reading to be interesting and compelling. This is a must read for anyone concerned about health and the path we need to be on to correct our problems. Highly recommended!
Scientist and author Martin Blaser does an excellent job of helping readers navigate the complex world of genomes, biomes, bacteria, viruses, and their complicated interactions and impacts on human health. He simplifies the material enough that it can be easily followed by a lay person while keeping it firmly rooted in solid science, research, and medicine. Shocking facts are sprinkled throughout (your average American gets more than 17 courses of antibiotics by age 20), but they are never used for shock value - merely reported in an honest, factual nature that keeps with the serious, professional tone of the book.
Blaser explores the long term consequences of heavy antibiotic use on individuals and society, and draws clear (and disturbing) links between overuse of antibiotics and modern plagues including diabetes, obesity, IBS/ulcerative colitis, asthma, and escalating food allergies. Using decades of sound scientific research and examples from both modern life and the history of medicine, he offers a slightly frightening but completely realistic picture of where we are headed as a planet if we don't change our ways. The book outlines key problems, offers viable (but not easy) solutions, and calls on all of us as a society to make better choices while we still can.
The book was a little on the dry side, but clearly written by a man passionate about his subject and it provides significant food for thought. An excellent read, and one we all do well to pay attention to!
This is now one of my favorite books! Give it a try!
As a study of microbiology, I would suggest this book to any first or second year students going into medical laboratory science as inspiring and eye-opening toward the next decade in medicine.
This was an enlightening view